Important Safety Information
Full Prescribing Information
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About
OMIDRIA
REAL-WORLD EVIDENCE
OMIDRIA significantly improved postoperative day 1 visual acuity across a wide age range¹
OMIDRIA PROVIDES AN IMPROVED PATIENT EXPERIENCE
Immediate improvement in postoperative visual acuity may be attributed to the anti-inflammatory properties of OMIDRIA.¹
Of the 641 eyes of 389 patients who underwent cataract surgery, 260 eyes were administered phenylephrine 1.0%/ketorolac 0.3% and 381 eyes received epinephrine in the irrigation solution intraoperatively.¹
All patients received a topical NSAID regimen for 3 days before surgery and topical tropicamide 1.0%, cyclopentolate 1.0%, and phenylephrine 2.5% on the day of surgery.¹
Single-center, retrospective case review (N=641)¹
OMIDRIA reduces pain during and after surgery
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The ketorolac component of intracameral OMIDRIA provides higher concentrations compared to topical drops²›³
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Fewer drops are needed for cataract surgery, so there is a less demanding routine for you, your staff, and your patients²
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OMIDRIA is easy to integrate into your surgical routine⁴
All patients received preoperative topical lidocaine gel for anesthesia, administered 2-3 times 15 minutes before surgery.⁵
At the start of the surgery, all patients received 0.5 mL of intracameral preservative-free lidocaine 1%.⁵Prospective, single-masked, comparative study (N=60)⁵
Preoperative treatments were standardized for all patients and included moxifloxacin 0.5% (Vigamox) treatment for at least 3 days before surgery, mydriatic treatment with topical phenylephrine HCl 2.5% plus tropicamide 1.0% three times in the 30 minutes before surgery, and lidocaine or tetracaine for local anesthesia on the day of surgery.⁶
Prospective, randomized, clinical trials (N=821)⁶
REFERENCES:
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Rosenberg ED, Nattis AS, Alevi D, et al. Visual outcomes, efficacy, and surgical complications associated with intracameral phenylephrine 1.0%/ketorolac 0.3% administered during cataract surgery. Clin Ophthalmol. 2018;12:21-28.
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Visco DM, Bedi R. Effect of intracameral phenylephrine 1.0%–ketorolac 0.3% on postoperative cystoid macular edema, iritis, pain, and photophobia after cataract surgery. J Cataract Refract Surg. 2020;46(6):867-872.
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Donnenfeld ED, Whitaker JS, Jackson MA, Wittpenn J. Intracameral ketorolac and phenylephrine effect on intraoperative pupil diameter and postoperative pain in cataract surgery. J Cataract Refract Surg. 2017;43(5):597-605.
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OMIDRIA [package insert]. Bellevue, WA: Rayner Surgical Inc. 2023.
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Donnenfeld ED, Shojaei RD. Effect of intracameral phenylephrine and ketorolac 1.0%/0.3% on intraoperative pain and opioid use during cataract surgery. Clin Ophthalmol. 2019;13:2143-2150.
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Hovanesian JA, Sheppard JD, Trattler WB, et al. Intracameral phenylephrine and ketorolac during cataract surgery to maintain intraoperative mydriasis and reduce postoperative ocular pain: integrated results from 2 pivotal phase 3 studies. J Cataract Refract Surg. 2015;41:2060-2068.
Indications and Usage
OMIDRIA® is added to ophthalmic irrigating solution used during cataract surgery or intraocular lens replacement and is indicated for maintaining pupil size by preventing intraoperative miosis and reducing postoperative ocular pain.
Important Safety Information
OMIDRIA must be added to irrigating solution prior to intraocular use.
OMIDRIA is contraindicated in patients with a known hypersensitivity to any of its ingredients.
Systemic exposure to phenylephrine may cause elevations in blood pressure.
Use OMIDRIA with caution in individuals who have previously exhibited sensitivities to acetylsalicylic acid, phenylacetic acid derivatives, and other nonsteroidal anti-inflammatory drugs (NSAIDs), or have a past medical history of asthma.
The most commonly reported adverse reactions at ≥ 2% are eye irritation, posterior capsule opacification, increased intraocular pressure, and anterior chamber inflammation.
Please see the Full Prescribing Information for OMIDRIA.
You are encouraged to report Suspected Adverse Reactions to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Indications and Usage
OMIDRIA® is added to ophthalmic irrigating solution used during cataract surgery or intraocular lens replacement and is indicated for maintaining pupil size by preventing intraoperative miosis and reducing postoperative ocular pain.
Important Safety Information
OMIDRIA must be added to irrigating solution prior to intraocular use.
OMIDRIA is contraindicated in patients with a known hypersensitivity to any of its ingredients.
Systemic exposure to phenylephrine may cause elevations in blood pressure.
Use OMIDRIA with caution in individuals who have previously exhibited sensitivities to acetylsalicylic acid, phenylacetic acid derivatives, and other nonsteroidal anti-inflammatory drugs (NSAIDs), or have a past medical history of asthma.
The most commonly reported adverse reactions at ≥ 2% are eye irritation, posterior capsule opacification, increased intraocular pressure, and anterior chamber inflammation.
Please see the Full Prescribing Information for OMIDRIA.
You are encouraged to report Suspected Adverse Reactions to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.